NHANES analysis shows that exposure to endocrine-disruptors may play a role in breast, ovarian, skin, and uterine cancers.

This study by Cathey et al., (2023) looked at NHANES data and showed that women with previous exposure to PFAs, phenols, and parabens had worse prognosis for endocrine-disruptor mediated cancers. High exposure to PFAs were linked to prior melanoma diagnoses.  PFA was also linked with prior uterine cancer diagnosis, while high phenol exposure was associated with ovarian cancer diagnosis. When they looked at race, they saw some PFAs were linked to ovarian and uterine cancers among white women, while other PFAs and phenols were only seen in breast cancer non-white women. There is some great data in this manuscript.  While we know race is a social construct, race can be a proxy for environmental exposures and disparities.

  1. Cathey AL, Nguyen VK, Colacino JR, et al. Exploratory profiles of phenols, parabens, and per- and poly-fluoroalkyl substances among NHANES study participants in association with previous cancer diagnoses. Journal of Exposure Science & Environmental Epidemiology, 2023; DOI: 10.1038/s41370-023-00601-6

Either use the DOI link or the direct link. https://www.nature.com/articles/s41370-023-00601-6#MOESM2